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Journal Watch Updates!
 
Extended follow-up reveals that first-line melphalan/prednisone plus thalidomide does not provide a survival advantage over melphalan/prednisone alone in patients ≥ 65 years with multiple myeloma.
June 27, 2008, 3:40 PM  Blood  PubMed

Clofarabine and low-dose cytarabine therapy demonstrated improved response rates and event-free survival compared to single-agent clofarabine in older patients with AML and high-risk MDS.
June 25, 2008, 3:03 PM  Blood  PubMed

Darbepoetin alfa raised hemoglobin levels and was well-tolerated in a phase II trial in patients with low-risk MDS.
June 25, 2008, 3:02 PM  Br J Haematol  PubMed

Mutational analysis as a prognostic tool in cytogenetically normal acute myeloid leukemia
May 8, 2008, 8:29 AM  N Engl J Med  PubMed

microRNA analysis for prognosis in cytogenetically normal acute myeloid leukemia
May 8, 2008, 8:29 AM  N Engl J Med  PubMed

Results from a phase III trial of darbepoetin alfa demonstrate shorter survival and no significant reduction in transfusion occurrence in patients with cancer-related anemia who were not receiving chemotherapy or radiotherapy.
April 17, 2008, 3:38 PM  J Clin Oncol  PubMed

High response rates and long-term overall survival were observed in patients with untreated chronic lymphocytic leukemia receiving fludarabine, cyclophosphamide, and rituximab.
April 17, 2008, 3:37 PM  Blood  PubMed

An IRIS study subanalysis demonstrated correlation between high imatinib plasma concentrations and good clinical outcomes
April 16, 2008, 4:09 PM  Blood  PubMed

Intensive high-dose rituximab-based sequential therapy (R-HDS) as first-line therapy provides superior complete remission rates and event-free survival but not overall survival compared to conventional CHOP-R regimen in patients with high-risk follicular lymphoma
April 16, 2008, 4:08 PM  Blood  PubMed

Complete and partial responses are observed in patients with relapsed/refractory CLL treated with lenalidomide, including those with high-risk and fludarabine-refractory disease.
April 4, 2008, 10:52 AM  Blood  PubMed